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Breaking down CKD by the numbers

CKD is a debilitating condition that often goes undiagnosed until late stages.

upto-850
The estimated global prevalence of CKD is >11%3 -~850 MILLION people with CKD4,5
upto-40
of people with T2D have CKD6,7
upto-60
of people with CKD have CV disease8

Clinical Insights

One test isn’t enough

When combined with eGFR, UACR allows healthcare professionals to stage and stratify the risk of CKD progression.

Leading organizations suggest using 2 tests

Using both urine albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) tests can help to completely screen for CKD in at-risk patients.1,2

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EARLY TESTING CAN MEAN EARLY TREATMENT

Detecting CKD early and starting treatment can help delay disease progression

  • Less than 20% of patients at risk for CKD between 2013 and 2019 received complete testing (defined as both eGFR and UACR) for CKD9

  • Only 10.5% of people with hypertension had complete testing9

  • SGLT2 inhibitors with documented kidney or cardiovascular benefit, ACE inhibitors, and ARBs are some of the recommended therapies for CKD10

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Why is it Important To Use e-GFR and UACR in Assessing CKD Patients?

References
  1. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. Kidney Int Suppl. 2024;105(4):S117-S314.

  2. American Diabetes Association Professional Practice Committee. Diabetes Care. 2024;47(Suppl. 1):S219-S230.

  3. Whelton PK, et al. Hypertension. 2018;71(6):1269-1324.

  4. ASN. The hidden epidemic: worldwide, over 850 million people suffer from kidney diseases. 2018. https://www.asn-online.org/news/2018/0626-Joint_Hidden_Epidem.pdf (accessed Mar 2023).

  5. Jager KJ, et al. Nephrol Dial Transplant. 2019;34:1803.

  6. Afkarian M, et al. JAMA. 2016;316:602.

  7. International Diabetes Foundation. Diabetes Atlas 9th Edition. http://www.diabetesatlas.org (accessed Mar 2023).

  8. Lovre D, et al. Endocrinol Metab Clin North Am. 2018;47:237.

  9. Alfego D, et al. Diabetes Care. 2021;44:2025-2032.

  10. American Diabetes Association Professional Practice Committee. Diabetes Care. 2025;48(Suppl. 1):S181-S206.